2026

Large language models for predicting one-year major adverse cardiovascular events in acute coronary syndrome
Large language models for predicting one-year major adverse cardiovascular events in acute coronary syndrome

X Zhang, L Shang, S Hou, J Li, K Yang, F Lai, P Tian, Y Zheng, G Su, T Xu

iScience 2026

A study on using large language models to predict one-year major adverse cardiovascular events in acute coronary syndrome.

Large language models for predicting one-year major adverse cardiovascular events in acute coronary syndrome

X Zhang, L Shang, S Hou, J Li, K Yang, F Lai, P Tian, Y Zheng, G Su, T Xu

iScience 2026

A study on using large language models to predict one-year major adverse cardiovascular events in acute coronary syndrome.

A unified framework enables accessible deployment and comprehensive benchmarking of single-cell foundation models
A unified framework enables accessible deployment and comprehensive benchmarking of single-cell foundation models

S Hou, P Yang, W Ma, JX Wang, X Zhou

bioRxiv preprint. 2026

A unified framework for deploying and benchmarking single-cell foundation models in a more accessible and reproducible way.

A unified framework enables accessible deployment and comprehensive benchmarking of single-cell foundation models

S Hou, P Yang, W Ma, JX Wang, X Zhou

bioRxiv preprint. 2026

A unified framework for deploying and benchmarking single-cell foundation models in a more accessible and reproducible way.

2025

Optimal transport modeling uncovers spatial domain dynamics in spatiotemporal transcriptomics studies
Optimal transport modeling uncovers spatial domain dynamics in spatiotemporal transcriptomics studies

W Ma, S Hou, L Shang, J Lu, X Zhou

bioRxiv preprint. 2025

A preprint using optimal transport modeling to characterize spatial domain dynamics in spatiotemporal transcriptomics.

Optimal transport modeling uncovers spatial domain dynamics in spatiotemporal transcriptomics studies

W Ma, S Hou, L Shang, J Lu, X Zhou

bioRxiv preprint. 2025

A preprint using optimal transport modeling to characterize spatial domain dynamics in spatiotemporal transcriptomics.

Meteorin-like protein inhibits vascular smooth muscle cell-derived foam cell formation and atherosclerosis via KIT-endoplasmic reticulum stress signaling
Meteorin-like protein inhibits vascular smooth muscle cell-derived foam cell formation and atherosclerosis via KIT-endoplasmic reticulum stress signaling

X Chen*, X Jiang*, S Hou*, F Lai, K Hu, J Li, T Yang, X Shen, H Chen (* equal contribution)

Metabolism 2025

A study on the role of meteorin-like protein in foam cell formation and atherosclerosis through KIT-endoplasmic reticulum stress signaling.

Meteorin-like protein inhibits vascular smooth muscle cell-derived foam cell formation and atherosclerosis via KIT-endoplasmic reticulum stress signaling

X Chen*, X Jiang*, S Hou*, F Lai, K Hu, J Li, T Yang, X Shen, H Chen (* equal contribution)

Metabolism 2025

A study on the role of meteorin-like protein in foam cell formation and atherosclerosis through KIT-endoplasmic reticulum stress signaling.

FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single-cell transcriptomics studies
FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single-cell transcriptomics studies

S Hou, W Ma, X Zhou

Nature Communications 2025

A scalable framework for robust cell-cell communication analysis in single-cell transcriptomics without costly permutation procedures.

FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single-cell transcriptomics studies

S Hou, W Ma, X Zhou

Nature Communications 2025

A scalable framework for robust cell-cell communication analysis in single-cell transcriptomics without costly permutation procedures.

2024

Phenylacetylglutamine accelerated endothelial senescence and early-stage atherosclerosis formation by modulating cholesterol synthesis
Phenylacetylglutamine accelerated endothelial senescence and early-stage atherosclerosis formation by modulating cholesterol synthesis

R Huang, X Jiang, S Hou, J Li

Circulation 2024

A conference abstract on phenylacetylglutamine, endothelial senescence, and early-stage atherosclerosis.

Phenylacetylglutamine accelerated endothelial senescence and early-stage atherosclerosis formation by modulating cholesterol synthesis

R Huang, X Jiang, S Hou, J Li

Circulation 2024

A conference abstract on phenylacetylglutamine, endothelial senescence, and early-stage atherosclerosis.

Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

T He, L Xiao, Y Qiao, O Klingbeil, E Young, XS Wu, R Mannan, S Hou, et al.

Cancer Cell 2024

A study on targeting the mSWI/SNF complex in transcription factor-driven malignancies.

Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

T He, L Xiao, Y Qiao, O Klingbeil, E Young, XS Wu, R Mannan, S Hou, et al.

Cancer Cell 2024

A study on targeting the mSWI/SNF complex in transcription factor-driven malignancies.

Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer

T He, C Cheng, Y Qiao, H Cho, E Young, R Mannan, S Mahapatra, S Hou, et al.

Proceedings of the National Academy of Sciences 2024

A study on an orally bioavailable mSWI/SNF ATPase degrader and resistance mechanisms in prostate cancer.

Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer

T He, C Cheng, Y Qiao, H Cho, E Young, R Mannan, S Mahapatra, S Hou, et al.

Proceedings of the National Academy of Sciences 2024

A study on an orally bioavailable mSWI/SNF ATPase degrader and resistance mechanisms in prostate cancer.

Cohort profile: A longitudinal multi-omics cohort of patients with acute coronary syndrome
Cohort profile: A longitudinal multi-omics cohort of patients with acute coronary syndrome

R Huang, J Li, K Hu, R Xu, H Yuan, J Wang, M Gao, Q Xiao, B Dong, S Hou

iMetaOmics 2024

A cohort profile describing a longitudinal multi-omics study of patients with acute coronary syndrome.

Cohort profile: A longitudinal multi-omics cohort of patients with acute coronary syndrome

R Huang, J Li, K Hu, R Xu, H Yuan, J Wang, M Gao, Q Xiao, B Dong, S Hou

iMetaOmics 2024

A cohort profile describing a longitudinal multi-omics study of patients with acute coronary syndrome.

2023

Metrnl Deficiency Destabilized the Atherosclerotic Plaque and Increased the Risk of Acute Coronary Syndrome
Metrnl Deficiency Destabilized the Atherosclerotic Plaque and Increased the Risk of Acute Coronary Syndrome

R Huang, F Lai, S Hou

Circulation 2023

A conference abstract on the role of Metrnl deficiency in plaque destabilization and acute coronary syndrome risk.

Metrnl Deficiency Destabilized the Atherosclerotic Plaque and Increased the Risk of Acute Coronary Syndrome

R Huang, F Lai, S Hou

Circulation 2023

A conference abstract on the role of Metrnl deficiency in plaque destabilization and acute coronary syndrome risk.

Development of attention-based robust deep learning model for tongue diagnosis by smartphone
Development of attention-based robust deep learning model for tongue diagnosis by smartphone

C Ma, C Gao, S Hou, S Li

bioRxiv preprint. 2023

A robust attention-based deep learning model for smartphone-based tongue diagnosis.

Development of attention-based robust deep learning model for tongue diagnosis by smartphone

C Ma, C Gao, S Hou, S Li

bioRxiv preprint. 2023

A robust attention-based deep learning model for smartphone-based tongue diagnosis.

2022

St2cell: Reconstruction of in situ single-cell spatial transcriptomics by integrating high-resolution histological image
St2cell: Reconstruction of in situ single-cell spatial transcriptomics by integrating high-resolution histological image

S Hou, K Tian, S Yang, J Xiang, W Yang, J Zhang, X Han

bioRxiv preprint. 2022

A preprint on reconstructing in situ single-cell spatial transcriptomics by integrating high-resolution histology images.

St2cell: Reconstruction of in situ single-cell spatial transcriptomics by integrating high-resolution histological image

S Hou, K Tian, S Yang, J Xiang, W Yang, J Zhang, X Han

bioRxiv preprint. 2022

A preprint on reconstructing in situ single-cell spatial transcriptomics by integrating high-resolution histology images.

Species composition and overall diversity are significantly correlated between the tongue coating and gastric fluid microbiomes in gastritis patients
Species composition and overall diversity are significantly correlated between the tongue coating and gastric fluid microbiomes in gastritis patients

J Cui, S Hou, B Liu, M Yang, L Wei, S Du, S Li

BMC Medical Genomics 2022

A study connecting tongue coating and gastric fluid microbiomes in gastritis patients through species composition and diversity analysis.

Species composition and overall diversity are significantly correlated between the tongue coating and gastric fluid microbiomes in gastritis patients

J Cui, S Hou, B Liu, M Yang, L Wei, S Du, S Li

BMC Medical Genomics 2022

A study connecting tongue coating and gastric fluid microbiomes in gastritis patients through species composition and diversity analysis.

Decoding multilevel relationships with the human tissue-cell-molecule network
Decoding multilevel relationships with the human tissue-cell-molecule network

S Hou*, P Zhang*, K Yang*, L Wang, C Ma, Y Li, S Li (* equal contribution)

Briefings in Bioinformatics 2022

A systems-level study that models multilevel relationships across tissues, cell types, and molecules in the human body.

Decoding multilevel relationships with the human tissue-cell-molecule network

S Hou*, P Zhang*, K Yang*, L Wang, C Ma, Y Li, S Li (* equal contribution)

Briefings in Bioinformatics 2022

A systems-level study that models multilevel relationships across tissues, cell types, and molecules in the human body.

2021

iMAP: integration of multiple single-cell datasets by adversarial paired transfer networks
iMAP: integration of multiple single-cell datasets by adversarial paired transfer networks

D Wang*, S Hou*, L Zhang, X Wang, B Liu, Z Zhang (* equal contribution)

Genome Biology 2021

A transfer-learning framework for integrating multiple single-cell datasets through adversarial paired networks.

iMAP: integration of multiple single-cell datasets by adversarial paired transfer networks

D Wang*, S Hou*, L Zhang, X Wang, B Liu, Z Zhang (* equal contribution)

Genome Biology 2021

A transfer-learning framework for integrating multiple single-cell datasets through adversarial paired networks.

2020

VISAR: an interactive tool for dissecting chemical features learned by deep neural network QSAR models
VISAR: an interactive tool for dissecting chemical features learned by deep neural network QSAR models

Q Ding, S Hou, S Zu, Y Zhang, S Li

Bioinformatics 2020

An interactive analysis tool for interpreting chemical features captured by deep neural network QSAR models.

VISAR: an interactive tool for dissecting chemical features learned by deep neural network QSAR models

Q Ding, S Hou, S Zu, Y Zhang, S Li

Bioinformatics 2020

An interactive analysis tool for interpreting chemical features captured by deep neural network QSAR models.